Almost every Fender Strat that I have played goes out of tune until you re cut the nut groves so that it doesn't pinch the strings.
Slacker -
Simplest solution I've found is a #2 pencil. Put some graphite in the nut slots when changing strings, intonation problems are minimized. Fender also made a gizmo called a Trem Setter a while back, I have one in my Squier Strat. It replaces the middle spring of the tremolo with a positive stop spring that lets the spring settle back to the same spot every time. Not perfect, but it helps, and the tremolo still works right. Both combined do a pretty good job.
String binding in the nut is usually caused by the strings themselves acting like little files. They cut into nut slots that might have been OK at first, but after a few months of regular gigging they cut their own grooves that are a perfect fit, allowing a greater chance of binding. If you want to stay on top of it, that can become a real problem, it only takes a couple of months of regular gigs to make a difference, and your nut slots get way too deep before long.
So the graphite is a pretty good solution, it acts as a lubricant, so the strings can slide better in the nut slots. I've kept a couple of pencils in my gear bags or guitar cases for at least 20 years. I never touch the nut slots, the graphite seems to be sufficient. Still have minor tuning problems, but usually either from temperature changes, (2 degrees can knock tuning out) or when I really romp on the whammy bar. In that case I know it's gone and I switch to a different guitar...if the temp stays constant, and I stay off the whammy bar, my Strat can stay in tune pretty well but is not as stable as my non tremolo guitars. Ditto for the Peavey Patriot.
A bone nut instead of the cheap plastic garbage they all use now is a good idea too, strings don't eat into bone as fast as plastic. I was not a happy camper when the nut on my Takamine broke during a string change and I found out my $800 guitar (Acoustic/electric and I got it for less than half that) had a cheap plastic nut...it has bone now...
I'm not sure what to think about the graphite nuts, I only have one, on the Peavey Patriot, (great guitar) and it seems to do ok but I still have to use a pencil on it same as the bone ones. Strings still bind and tuning is out the window.
Mike - I've done that for years, I noticed it long ago when trying out guitars. No need to plug in, just wanted to see how they play first. My left hand cannot handle a fat guitar neck due to a tendon injury, so 30 seconds and I know if the neck is too fat. (Gibsons are almost always too fat, especially LPs) Why bother plugging in if I won't be playing it longer than that? I quickly found out that the ones that sounded dead unplugged never sounded great plugged in, I started using that every time same as JW. If it sounds dead and lifeless unplugged, I put it back on the rack, it never gets plugged in.
A couple of times that has gotten me some dirty looks from salesmen...play a guitar for a minute or so, put it back and the salesman is trying to sell it...tell him nope, sounds like crap...$1500 guitar, he's looking at $$$ commission flying out the window...and I tell him it sounds like crap...but if it doesn't have the sound and sustain I'll know it, and I'm not looking any further. Someone else can worry about his commission...A couple have told me "but you haven't even listened to it"...Yes I did bud, and I don't need to hear it through an amp. Usually I'm already picking up another one...too late...
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