When I purchase any instrument, if I am not happy with the sound it is of little value to me. I don't care what it costs, I am not in the collector business, I am a musician. If I like the guitar and don't care for the sound, I will change the sound.
The first thing I do is play with it for a while. If I can't get a sound that I want, I change the pickups. Hardly any of my guitars have OEM pickups. I prefer Mexican Strat pickups to American Strat pickups because they have been a bit more powerful and have more of a midrange edge to them. However, I most always save the pickups that I have exchanged in case I should develop a different taste down the line.
As far as bass pickups, I have found that most OEM pickups are fairly good. At least until I find them noisy or anemic. An instrument that doesn't sound like I want it to or play good is useless to me.
Collector value means nothing unless you find some idiot who is ready to pay an absurd price for something just because it is old.
But on the other hand, Jesus or Mary potato chips rake in a fortune if you get someone stupid enough to buy them. Go figure.
I would never alter a Jesus potato chip.